FILE: /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/Application/Home/Controller/PraiseController.class.php LINE: 56
名称: | 仅有重链的抗BCMA抗体 |
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申请号: | CN201880038588 |
申请日期: | 2018-06-20 |
申请人: | |
发明人: | N·特林克林; S·F·奥尔德雷; S·克拉克; W·范斯科顿 |
地址: | 美国加利福尼亚 |
主分类号: | C07K16/28 |
分类号: | C07K16/28 |
主权项: | 1.一种与人B细胞成熟抗原(BCMA)结合的仅有重链的抗体,所述抗体包含含有以下序列的重链可变区: (a)在SEQ ID NO:1至7的氨基酸序列中的任一个中具有2个或更少的取代的CDR1;和/或(b)在SEQ ID NO:8至11的氨基酸序列中的任一个中具有2个或更少的取代的CDR2;和/或(c)在SEQ ID NO:12至15的氨基酸序列中的任一个中具有2个或更少的取代的CDR3。 |
摘要: | 公开了仅有重链的抗BCMA抗体(UniAb)以及制备此类抗体的方法,包括药物组合物在内的包含此类抗体的组合物,及其在治疗以BCMA表达为特征的B细胞病症中的用途。 |
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2020-03-31 | 公开 | js/timeglider/js/timeglider/icons/verticalLineGray.png | 50 |
:( FILE: /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/Application/Home/Controller/PraiseController.class.php LINE: 56 #0 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/Application/Home/Controller/PraiseController.class.php(56): Yar_Client->__call('theme_bar', Array) ThinkPHP3.2.3 { Fast & Simple OOP PHP Framework } -- [ WE CAN DO IT JUST THINK ]curl exec failed 'Timeout was reached'
错误位置
TRACE
#1 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/Application/Home/Controller/PraiseController.class.php(56): Yar_Client->theme_bar('get_bar_id', Array)
#2 [internal function]: Home\Controller\PraiseController->get_bar_id_by_from_id()
#3 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/ThinkPHP/Library/Think/App.class.php(173): ReflectionMethod->invoke(Object(Home\Controller\PraiseController))
#4 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/ThinkPHP/Library/Think/App.class.php(110): Think\App::invokeAction(Object(Home\Controller\PraiseController), 'get_bar_id_by_f...')
#5 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/ThinkPHP/Library/Think/App.class.php(204): Think\App::exec()
#6 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/ThinkPHP/Library/Think/Think.class.php(120): Think\App::run()
#7 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/ThinkPHP/ThinkPHP.php(97): Think\Think::start()
#8 /home/ftp/1520/ipa361_com-20150420-MrH/ipa361.com/mapi/index.php(27): require('/home/ftp/1520/...')
#9 {main}